Benzodiazepines alter cochleo-cochlear loop in humans.
نویسندگان
چکیده
By using otoacoustic emission, we looked for change in outer hair cell (OHC) motile activity and medial olivocochlear (MOC) system inhibition due to benzodiazepine administration, a drug that is known to produce a pharmacological effect by interacting with GABAergic inhibitory neurotransmission. No effect was observed on OHC motile activity, in contrast benzodiazepines decreased MOC system effectiveness suggesting the existence of GABAergic fibers projecting onto the MOC system.
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ورودعنوان ژورنال:
- Hearing research
دوره 121 1-2 شماره
صفحات -
تاریخ انتشار 1998